For Sponsors and CROs

San Antonio Riverwalk Water


Progressive Clinical Research is an independent research site dedicated to the performance of quality pharmaceutical research. We give each study the important personal attention it deserves. The Principal Investigators and the study team are intimately involved with the day-to-day operation of performing a successful clinical trial. Progressive Clinical Research has worked with many central IRBs and our regulatory specialist is able to turn around start-up documents within 1- 2 weeks. Contracts and budgets are also generally agreed upon within 1- 2 weeks. We pride ourselves on rapid study start-up and quality data collection.


Mark S. Lee, M.D. is the Medical Director of Progressive Clinical Research. He received the Doctor of Medicine degree from the George Washington University School of Medicine in Washington, D.C. and completed his residency training in Dermatology at the Brooke Army Medical Center in San Antonio. He is board-certified in Dermatology and has been involved in clinical research for 15 years. Dr. Lee has conducted over 125 studies.

Theresia L. Lee, M.D. is the Assistant Medical Director of Progressive Clinical Research. She received the Doctor of Medicine degree from the George Washington University School of Medicine in Washington, D.C. and completed her residency training at the Mayo Clinic. She is board-certified in Pain Medicine and Anesthesiology. Dr. Lee has been practicing in San Antonio for over 15 years. She is a Certified Principal Investigator by the Association of Clinical Research Professionals (ACRP).


Our facility maintains a double-locked, secured, temperature-monitored storage site for study drugs. We have -20˚C and -70˚C freezers, a refrigerated centrifuge, EKG, phlebotomy, internet access, and monitoring room on site. 


The San Antonio area population is approximately 1.5 million.

  • Progressive Clinical Research draws from all of South Texas.
  • Hispanics comprise 63% of the population.
  • Clinical research is well received in the local community.

Therapeutic Indications


Acne, Actinic Keratosis, Alopecia, Atopic Dermatitis, Eczema, Bacterial Skin Infections, Basal Cell Carcinoma, Hand Dermatitis, Herpes Labialis, Herpes-Genital, Hydroadenitis Suppurativa, Hyperpigmentation, Molluscum Contagiosum, Onychomycosis, Photodamage, Psoriasis, Rosacea, Seborrheic Dermatitis, Tinea Capitis, Tinea Cruris, Tinea Pedis, Tinea Versicolor, Warts-Common, Warts-Genital, Warts-Plantar

Pain Medicine/Other

Chronic Low Back Pain, Fibromyalgia, Osteoarthritis-Hip, Osteoarthritis-Knee, Peripheral Neuropathy, Post-Herpetic Neuralgia, Female Contraception


Our experienced physicians and nurse coordinators have conducted phase I, II, III, and IV clinical trials for over 15 years. The Principal Investigators have conducted over 125 trials. Progressive Clinical Research has three full-time clinical research coordinators. With the Principal Investigators, the study team has conducted clinical trials using narcotic study drugs, intravenous (IV) study drugs, subcutaneous (SQ) study drugs (shots), as well as topical and oral study drugs. Our site has extensive experience with numerous subject questionnaires, investigator assessments, photography (whole body and targeted areas), quantiferon gold, patch tests, skin biopsies, pK samples, PASI, NAPSI, EASI, SCORAD, EDC, IVRS/IWRS, and electronic diaries.

If we can collaborate with you on your next clinical trial, or for more information please contact us.